When you suffer an injury, it causes an inflammatory reaction inside the body, and if the problem isn’t treated correctly, this inflammation can linger. The prevailing understanding when it comes to chronic pain is that it is caused by chronic inflammation, which is why many specialists try to prevent the problem by working to control inflammation. Anti-inflammatory medication like Ibuprofen has been a common recommendation for decades as a way to effectively manage inflammation and work to reduce the risk of it becoming chronic.
However, new research seems to suggest that attempting to drown out this inflammation with anti-inflammatory medications before it gets out of control may not be providing the benefits we assume it does. In fact, they believe short-term use of these Non Steroidal Anti-Inflammatory Drugs (NSAIDs) may actually increase your risk of chronic pain in the long term, and that claim is dividing the medical world.
Ibuprofen And Chronic Pain
The new research suggests that the initial inflammation that develops after an injury may be necessary for the body to make a full recovery. If this suggestion is true, it could shatter the decades-old standard of treating pain with aspirin, ibuprofen or IV steroids at the hospital. By drowning out this necessary initial inflammation, researchers suggest NSAIDs may actually be putting patients at a greater risk for developing chronic pain.
“For many decades it’s been standard medical practice to treat pain with anti-inflammatory drugs. But we found that this short-term fix could lead to longer-term problems,” says Jeffrey Mogil, a Professor in the Department of Psychology at McGill University and E. P. Taylor Chair in Pain Studies. “Neutrophils dominate the early stages of inflammation and set the stage for repair of tissue damage. Inflammation occurs for a reason, and it looks like it’s dangerous to interfere with it.”
Now, it’s worth noting that not everyone agrees with the research, at least not without additional evidence. The paper was rejected from the New England Journal of Medicine after one reviewer wrote that he would not “overturn decades of medical practice,” until additional convincing evidence was presented.
Even if the findings are true, as we’ve said countless times on our blog in the past, it may only hold true for a subset of patients because chronic pain is so unique to the individual, and what works for one patient may not work for others. For example, the shock and inflammatory response of an ankle sprain and a surgery vary greatly, and assuming this research applies unilaterally to both of these groups could lead people down the wrong treatment path.
So while the jury is still out on whether or not NSAIDs may be having some unintended consequences for our ability to help pain resolve, the good news is more research is being poured into how to best handle chronic pain, and that’s a great thing. The more we learn, the better we can help each patient.
If you need help with a chronic pain issue, reach out to Dr. Cohn’s office today at (952) 738-4580.
Nonsteroidal anti-inflammatory drugs (NSAID) are the most commonly prescribed drugs in the world. Generally they are safe medications and they are often available as over-the-counter (OTC) items. The risks and benefits of these drugs are often misunderstood. Taking too much is common; not taking enough to be effective may also be an issue. The directions on how to take the drugs do vary depending on the exact compound. Furthermore, every drug has different strength, so a small amount of one drug could be stronger than a big pill of another one. Lastly, some drugs have unique delivery systems, such as they are available in creams to put on the skin.