Could Non-Invasive Brain Procedure Help Solve Chronic Pain?

ultrasound brainResearchers out of Virginia Tech are exploring the possibility of using targeted soundwaves to put an end to chronic pain sensations.

According to the research published in the journal PAIN on Feb. 5, researchers believe that low-intensity soundwaves aimed at a place deep in the brain called the insula could positively impact the perception of pain as well as some of the bodily effects of chronic pain, like heart rate variability.

““This is a proof-of-principle study,” said study lead author Wynn Legon, an assistant professor at the Fralin Biolmedical Research Institute at Virginia Tech. “Can we get the focused ultrasound energy to that part of the brain and does it do anything? Does it change the body’s reaction to a painful stimulus to reduce your perception of pain?”

Harnessing Ultrasound Technology

Ultrasound technology is commonly associated with the ability to view a baby inside a mother’s womb, but it has plenty of other helpful medical uses. High intensity ultrasound can ablate tissues, while low intensity soundwaves can alter electrical activity within a nerve. The latter was the idea behind Legon’s latest study.

For the study involving 23 patients, researchers applied heat to the back of their hands to induce discomfort. At the same time, a wearable headpiece delivered focused ultrasound waves to a specific spot in their brain that was guided by magnetic resonance imaging. Participants were asked to rate their pain perception during each application from zero to nine. At the same time, researchers monitored a person’s heart and heart rate variability, which can help to interpret the body’s reaction to painful stimulus.

When the soundwaves were administered, participants reported an average reduction in pain of three-fourths of a point.

“That might seem like a small amount, but once you get to a full point, it verges on being clinically meaningful,” said Legon. “It could make a significant difference in quality of life, or being able to manage chronic pain with over-the-counter medicines instead of prescription opioids.”

The study also found that the ultrasound application reduced the measured physical responses to the stress of pain – heart rate and heart rate variability.

“Your heart is not a metronome. The time between your heart beats is irregular, and that’s a good thing,” Legon said. “Increasing the body’s ability to deal with and respond to pain may be an important means of reducing disease burden.”

Although the research is in its infancy, it presents a new angle for tackling the issue of chronic pain. Hopefully future studies will find similar results, as a non-invasive and non-addictive treatment is the ideal answer to the problem of chronic pain.

For now, if you’re looking for a more traditional way to overcome your chronic pain condition, sync up with Dr. Cohn and his team. For more information, or for help with a specific chronic pain issue, reach out to Dr. Cohn’s office today at (952) 738-4580.